Casodex - racemic mix, a nonsteroid anti-androgen which does not influence endocrine system in any way. The mechanism of effect of active component consists in its ability to contact androgenic receptors of "wild type" and to oppress the activity, thereby, bringing a prostate tumor into a regression stage. Casodex is taken as a medicine for monotherapy, and as a part of complex treatment (radiation).
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Drug Uses
Casodex is a nonsteroidal anti-cancer drug that provides antiandrogen activity. Casodex tablets are used for oral therapy of metastatic carcinoma of the prostate (advanced prostate cancer) and are not effective in the treatment of other types of cancer.
To inhibit a growth of tumor cells and shrink tumors in advanced prostate cancer, Casodex tablets should be used in combination with anticancer agents of the group of LHRH analogues. In addition, Casodex can be prescribed for regression of metastatic prostate cancer (Stage D2) after surgical castration.
In order to slow down the growth and division of cancer cells in the prostate gland, Casodex tablets should be taken regularly once a day. Increase in the frequency of Casodex use does not provide extra benefits while treating prostate cancer.
Missed Dose
If you forget to take Casodex pills at the scheduled time, take the next dose of this antiandrogen agent as prescribed. However, do not take two doses of Casodex to make up the missed dose of this anticancer drug.
More Information
Immediately after the start of LHRH analogue therapy, the disease symptoms can be exacerbated in men with prostate cancer. Casodex tablets are able to prevent adverse effects arising after the administration of LHRH analogue. Therefore, Casodex therapy should be started a few days before the first use of an implant or injection of LHRH analogue.
Storage
Casodex tablets should be stored in a dry place, at room temperature not exceeding 30°C.
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Warnings
In men with impaired hepatic function, Casodex can be accumulated in the body and cause the drug-induced liver injury in a long-term use. The men with moderate to severe hepatic dysfunction are at higher risk of liver damage than the men with healthy liver or mild liver diseases. Therefore, the men who have serious liver problems should use Casodex with caution. If signs of serious hepatic dysfunction (including jaundice) arise, the use of Casodex tablets should be discontinued.
Disclaimer
Material about anticancer drugs published in Casodex review is provided for informational purposes only and does not supersede all previous medical advice you have received from the oncologist, urologist or other physicians. Using the information provided about anticancer therapy, you agree that the online pharmacy is not responsible for any loss or damage of any nature arising from the use of any material of the Casodex review.
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Approximately 50% of men using Casodex for prostate cancer may experience hot flashes. Casodex may increase a risk of constipation, asthenia, anemia, nausea, peripheral edema, abdominal pain, haematuria, nocturia, diarrhea and dyspnea in approximately 10% of men.
During the treatment with Casodex, less than 10% of men may experience flatulence, rash, gynecomastia, dyspepsia, dizziness, appetite disorders, chest pain and erectile dysfunction. Casodex tablets may cause liver dysfunction in some men.
Almost all side effect of Casodex are reversible and rapidly disappear after cessation of the combined treatment of advanced prostate cancer. Despite the large number of side effects that Casodex may cause, the benefits of this anticancer drug exceed the potential risks.
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