An antimicrobial agent from the nitrofurans group, especially suitable for the treatment of urinary tract infections and prevention of infections after urologic surgery or examinations (cystoscopy, catheterization, etc.). The medicine disrupts the permeability of the cell membrane and protein synthesis in bacteria.
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Drug Uses
Macrobid is a drug with antimicrobial activity, a synthetic antibiotic from the class of nitrofurans, used to treat urinary tract infections.
This antibacterial agent is effective against Gram-positive and Gram-negative bacteria, such as Staphylococci, Escherichia coli, Streptococcus, Klebsiella and Citrobacter. When used in low doses, Macrobid usually exerts bacteriostatic effect on the microorganisms, while as in high doses it can exert a bactericidal effect.
The antibacterial agent Macrobid is prescribed to adults and pediatric patients (including infants, from the second month of life) for the treatment and prophylaxis of infections in the bladder, kidney and other parts of the urinary tract.
The therapeutic dose of Macrobid for the treatment of lower urinary tract infections in pediatric patients is adjusted depending on the child's weight. The daily dosage for patients in this age group is between 5 and 7 mg per kg of body weight, divided into 4 doses. The daily dose of this antibacterial agent for adults and children of 12 years and older is one Macrobid 100mg capsule every 12 hours, 7 days in a row.
Missed dose
Take the missed dose of Macrobid, as soon as you remember. But do not take it at all, if it is nearly time for your next dose of the antibiotic. Then go back to the regular dosing schedule of the antibacterial agent.
More Information
Most strains of Proteus, Pseudomonas species or Serratia species are not sensitive to Macrobid, so this antibacterial is not recommended for the treatment of urinary tract infections, caused by these microorganisms. Macrobid is not recommended for the treatment of perinephric abscesses, pyelonephritis, any systemic infections, or in prostatitis.
Storage
Antibacterial agent Macrobid should be kept in its original package to protect from moisture at controlled room temperature of 20°C to 25°C.
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Warnings
Macrobid should be discontinued, if lung diseases of varying severity develop in the patient. Using antibacterial agent for more than 24 weeks increases the risk of such disorders, as the interstitial lung disease or scarring of the lungs, which may lead to death.
Disclaimer
All information about the treatment of urinary tract infections, provided in the review of Macrobid, is general information, provided for educational purposes. All information materials are not intended or implied to be a substitute for professional medical advice of an urologist, gynecologist or other health professional. In no event shall the online pharmacy be liable for any damages, resulting from the use or inability to use material on the antibacterial agent, contained in the review on Macrobid.
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Adverse effects of Macrobid are usually mild and do not require discontinuation of the antibiotic. The antibacterial agent most common causes nausea, anorexia, pancreatitis, emesis, flatulence, indigestion, sialoadenitis, headache, hair loss, itch, polyneuropathy, leukopenia or somnolence. Less commonly, the patients taking Macrobid, may notice pseudomembranous colitis, hepatitis, cholestatic jaundice, cough, shortness of breath, optic neuritis, weakness, vertigo, depression, euphoria, confusion, fever, eosinophilia, or shivering.
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